“Important health information. » Here is the title of a letter received by several women in recent weeks from the National Agency for the Safety of Medicines and Health Products (ANSM) regarding their treatment. The latter warns them about the use of the progestin medrogestone, known as Colprone, which can promote the development of a meningioma. What does this treatment consist of? What are its risks? What to do if you take it? We answer these questions.
What is Colprone?
This medication containing a hormone close to progesterone is used in the treatment of various gynecological disorders, in particular those linked to progesterone insufficiency: cycle irregularity, premenstrual syndrome, breast tension, painful periods, bleeding (especially those due to fibroid), endometriosis or even menopause.
What are its risks?
The ANSM explains that it is an “effective drug but which can promote the development of a meningioma”, a tumor developed from the membrane which surrounds the brain. “Most often these tumors are non-cancerous, however they can cause serious problems, which may require major surgical intervention,” continues the agency. The ANSM specifies that the risk of developing a meningioma increases depending on the duration of treatment. “A study has shown that the risk of developing a meningioma is multiplied by 4 for medrogestone after one year of treatment. »
What should I do if I take it?
The ANSM invites women who have taken this treatment to consult their doctor “without urgency”. “He will judge whether or not it is necessary to carry out brain imaging (MRI). » However, if the medication has been taken for more than twelve months, the agency recommends carrying out this medical examination to look for a meningioma. And if the treatment is taken for several years, the agency advises regular MRI.
For any renewal of medrogestone, an information sheet must be given to the patient. If the treatment is taken for more than twelve months, she must co-sign this certificate with her doctor every year. “It is essential to obtain your medicine in pharmacies after one year of treatment,” explains the ANSM.
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Finally, in the event of symptoms that could suggest a meningioma, such as frequent headaches, vision, language, hearing or memory problems or dizziness, it is imperative to consult your doctor. If a meningioma is discovered, the use of progestin should be stopped immediately.